Depo-Provera is given as a shot in your upper arm or hip. It consists of progesterone which is released into your system over a period of three months. It prevents ovulation. It provides highly effective contraception for three months. It is a popular method of contraception among nursing moms since it is safe for breast feeding and does not decrease the milk supply. The most common side effects are irregular spotting, a small weight gain, or a delay in return of fertility beyond the three months of use.